Over 100 artists and entertainers took part in Lady Gaga's One World: Together At Home event, organized with the World Health Organization and the Global Citizen social action group to help fight the COVID-19 pandemic.

Lady Gaga kicked off the telecast with a soulful performance of "Smile," a classic popularized by Nat King Cole and Jimmy Durante.

"I'm so grateful for the health-care workers, the medical workers, all the grocery store workers and delivery people, the postal workers, all the other non-profits that are working so hard," Gaga said.

"This is really a true love letter to all of you all over the world, and I hope a reminder of the kindness that's occurring right now," she added.

The event was not a fundraiser, Gaga said, as the money had been raised in advance of the show: "Put your wallets away and sit back and enjoy the show." Gaga has so far helped raise over $50 million from corporations such as Apple, IBM, and Verizon, and will continue accepting donations

Together At Home featured performances from such acts as The Rolling Stones, Jennifer Lopez, Billie Eilish, Taylor Swift, Lizzo, Shawn Mendes, Camilla Cabello, Elton John, Billie Joe Armstrong, and more.

For the closing performance, Gaga joined Andrea Bocelli, Celine Dion, John Legend, and Lang Lang for a stunning rendition of "The Prayer." 

Watch Gaga's performances, as well as the full special, below...