RAMROD 117,983 Posted January 28 Share Posted January 28 A Spanish research team says it has developed a treatment that completely eliminated the most aggressive form of pancreatic cancer in laboratory mice, raising fresh hopes against one of the deadliest cancers. The study, led by Mariano Barbacid at Spain’s Spanish National Cancer Research Centre, found that a newly designed triple-drug therapy wiped out pancreatic tumours with no relapse seen after treatment. After six years of work, researchers reported that the animals showed minimal side effects and no tumour recurrence, results that mark one of the most promising advances yet in pancreatic cancer research. Pancreatic cancer, particularly pancreatic ductal adenocarcinoma, is among the deadliest malignancies due to its resistance to treatment, dense tumour microenvironment, and late diagnosis. Standard therapies often fail because tumours rapidly adapt, bypassing single-target drugs.The CNIO therapy takes a different approach. Instead of attacking one pathway, it combines three drugs to shut down multiple tumour survival mechanisms simultaneously. According to the researchers, this strategy prevents cancer cells from rewiring themselves, a common cause of treatment failure.Barbacid has previously argued that pancreatic cancer cannot be defeated with a single-drug strategy.This tumour, he has said in earlier research discussions, is extraordinarily adaptable, and only coordinated inhibition of multiple pathways can produce lasting responses. The research was conducted at CNIO, one of Europe’s leading cancer research institutions, with support from Fundación CRIS Contra el Cáncer, which funds high-risk, high-impact cancer research projects.The study followed established experimental protocols and underwent independent peer review before publication. There is no evidence the findings were rushed or bypassed scientific safeguards, a point emphasised by CNIO officials amid online speculation. https://timesofindia.indiatimes.com/science/spanish-scientist-finds-cure-for-pancreatic-cancer-in-major-medical-breakthrough/articleshow/127714543.cms (ノ◕ヮ◕)ノ✧*:・゚ ⁱᵐ'ᵐᵃ ʰⁱᵗ ᵈᵉᶠʳᵒˢᵗ ᵒⁿ ʸᵃ, ˡᵉᵗ'ˢ ᵍᵉᵗ ⁱᵗ ᵇˡᵃᶻⁱⁿᵍ﹗ (*´艸`*) ♡♡♡ 5 6 1 Quote Link to post Share on other sites More sharing options...
TheFrenchGuy 5,888 Posted January 28 Share Posted January 28 Good news ? In this economy? Quote Link to post Share on other sites More sharing options...
LGAte 1,158 Posted January 28 Share Posted January 28 YES! I love positive stories like this. We need to remind people of the light. Stay aware of all the darkness and stay aware of all the potential for light. 1 Quote Link to post Share on other sites More sharing options...
Economy 53,089 Posted January 28 Share Posted January 28 This is awesome but it sounds like this still needs confirmation in human testing as sometimes the results in humans is not always the same as in mice. The title made me think the cure was already definite and confirmed. Still tho, great progress! 1 Quote Link to post Share on other sites More sharing options...
DopeEnigma 1,816 Posted January 28 Share Posted January 28 A rare positive story, I really hope this can be the case all the way through the trials, F*** Cancer, there is hope 🤞🏻 1 Quote Link to post Share on other sites More sharing options...
Nano 3,744 Posted January 28 Share Posted January 28 A company called Elicio Therapeutics is working on pancreatic cancer and has promising data from humans in an early clinical trial https://www.nature.com/articles/s41591-025-03876-4 https://chaotropy.substack.com/p/elicios-therapeutic-vaccine-for-pancreatic?r=6gqh0d&utm_medium=ios&shareImageVariant=overlay&triedRedirect=true You chew beef, I wear meat. 2 Quote Link to post Share on other sites More sharing options...
Economy 53,089 Posted January 28 Share Posted January 28 Also side note. This is from Spain and according to Trump... "wE DoNt nEEd aNyThiNg FroM oTheR cOUnTrIeS" I hope (not really, but kinda) that Trump gets pancreatic cancer and needs to search out treatment from Spain not USA. This would REALLY hurt his fragile ego and id be here for it Quote Link to post Share on other sites More sharing options...
high culture 2,376 Posted January 28 Share Posted January 28 My best friends mom and uncle both passed from pancreatic cancer. This is great news Quote Link to post Share on other sites More sharing options...
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