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UCLA Found Way To Kill HIV Cells Inside Individuals


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A UCLA-led team of researchers believe they may have found a way to kill HIV-infected cells inside infected individuals, opening a “new paradigm for a possible HIV cure in the future,” the study's lead author said Monday.

The breakthrough could potentially reduce, if not eliminate, the virus from the currently 38-million people around the world who have HIV, according to UCLA.

Researchers developed a “kick and kill” strategy of using cells that are naturally produced in the immune system to kill infected cells hiding inside the body, which could potentially eradicate them, according to the study's lead author Dr. Joceyln Kim, assistant professor of medicine in the division of infectious diseases at the David Geffen School of Medicine at UCLA .

“These findings show proof-of-concept for a therapeutic strategy to potentially eliminate HIV from the body, a task that had been nearly insurmountable for many years,” Kim said. “This study opens a new paradigm for a possible HIV cure in the future.”

By lying dormant in some cells, HIV can elude anti-retroviral medications. When a person who is infected with HIV stops treatment, the virus emerges and replicates in the body, which weakens the person's immune system and raises the chance of opportunistic infections or cancers, which can sicken or kill the person. Tens of millions of people have died from HIV-related
diseases in the decades since the virus was discovered.

In that study, up to 25% of the previously dormant cells died within 24 hours of activation. However, researchers concluded they needed a more effective way to kill the cells, so in this study they used the same synthetic compound to flush HIV infected cells out of hiding and then inject healthy natural killer cells into the mice's bloodstreams to kill the infected cells. The new method cleared HIV in 40% of the HIV-infected mice, and the researchers couldn't detect the virus in the mice's spleens, which suggests that cells harboring HIV were eliminated.

The study received funding from the National Institutes of Health, the American Foundation for AIDS Research, the National Science Foundation, the National Center for Advancing Translational Sciences UCLA CTSI Grant, the UCLA Center for AIDS Research, the UCLA AIDS Institute and the McCarthy Family Foundation.
 

https://www.audacy.com/knxnews/news/local/ucla-led-team-may-have-found-way-to-kill-hiv-infected-cells

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This is exciting news, hope the team keeps the good work and also keep that percentage  of killed cells increases by the day, god bless them

... and now i just sit in silence.
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LeJudas

When I finally join the teams researching these amazing promising medicine breakthroughs I will be unstoppable 

:vegas: 

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Economy

Crossing my fingers

 

But im also being cautios in hype as a lot of promising treatments at first never seem to end up being developed

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HEARTSTOP

Sounds expensive. Either way, this doesn't prevent re-infection, which doesn't change much for the general population. I'm glad there is at least a glimmer of hope for those who have to live with this terrible disease.

IDGAF
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StarstruckIllusion
34 minutes ago, HEARTSTOP said:

Sounds expensive. Either way, this doesn't prevent re-infection, which doesn't change much for the general population. I'm glad there is at least a glimmer of hope for those who have to live with this terrible disease.

Girl what 💀 Who cares about a reinfection… just get the cure again. This is revolutionary and will change so much for the GP. Being HIV positive can be such a life altering thing so to say this doesn’t change much… 💀

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HEARTSTOP
3 hours ago, StarstruckIllusion said:

Girl what 💀 Who cares about a reinfection… just get the cure again. This is revolutionary and will change so much for the GP. Being HIV positive can be such a life altering thing so to say this doesn’t change much… 💀

If you think this is an easy-peasy treatment, you're being naive. I'm sure this has a lot of bad side effects that makes it so you can't simply "get the cure again". I'm thinking something along the lines of chemotherapy, or maybe even more aggressive. You're artificially killing your cells after all.

What I'm saying is that people should still use protection and be careful, even when this treatment is eventually available.

The invention of PrEP was such a modern miracle but the gays(TM) took it to the extreme right away with risk behaviors that made other STDs spread even faster. If people get the idea this treatment is an "easy thing" that solves all your problems and you can just get it whenever you want, it certainly will have bad repercussions in other parts of their (sexual) health. And yes, I know not all gays are the same OBVIOUSLY, but many (especially in the gay club scene) like to push the limits due to bad sexual education, or just irresponsibility.

IDGAF
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