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Pfizer COVID pill 89% effective


alsemanche

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alsemanche

Nov 5 (Reuters) - A trial of Pfizer Inc's (PFE.N) experimental antiviral pill for COVID-19 was stopped early after the drug was shown to cut by 89% the chances of hospitalization or death for adults at risk of developing severe disease, the company said on Friday.

Pfizer said it plans to submit interim trial results for its pill, which is given in combination with an older antiviral called ritonavir, to the U.S. Food and Drug Administration as part of the emergency use application it opened in October.

The combination treatment, which will have the brand name Paxlovid, consists of three pills given twice daily.

The planned analysis of 1,219 patients in Pfizer's study looked at hospitalizations or deaths among people diagnosed with mild to moderate COVID-19 with at least one risk factor for developing severe disease, such as obesity or older age.

It found that 0.8% of those given Pfizer's drug within three days of symptom onset were hospitalized and none had died by 28 days after treatment. That compared with a hospitalization rate of 7% for placebo patients. There were also seven deaths in the placebo group.

Rates were similar for patients treated within five days of symptoms - 1% of the treatment group was hospitalized, compared with 6.7% for the placebo group, which included 10 deaths.

The company did not detail side effects of the treatment, but said adverse events happened in about 20% of both treatment and placebo patients.

https://www.reuters.com/business/healthcare-pharmaceuticals/pfizer-says-antiviral-pill-cuts-risk-severe-covid-19-by-89-2021-11-05/ 

Soft, soothing, and succulent
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Gabi001

Great news, but when will they give so much money and energy into HIV treatment and vaccine? 

I'm not having fun tonight.
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alsemanche
38 minutes ago, Gabi001 said:

Great news, but when will they give so much money and energy into HIV treatment and vaccine? 

They're advancing in their trials for HIV treatments and I think they've made considerable progress this year, but yeah I agree they need to put a lot more time and funds into HIV research. It's been way too long and it really shouldn't take that long. 

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gagawaffles
39 minutes ago, Gabi001 said:

Great news, but when will they give so much money and energy into HIV treatment and vaccine? 

You’re joking right? HIV has tons of research and there are many anti-retrovirals… 

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liquidsunshine

 

1 hour ago, Gabi001 said:

Great news, but when will they give so much money and energy into HIV treatment and vaccine? 

HIV vaccine trail has already started. It needed a breakthrough in RNA discovery which just happened. 

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JohnWayne92
28 minutes ago, liquidsunshine said:

 

HIV vaccine trail has already started. It needed a breakthrough in RNA discovery which just happened. 

I don’t believe the break through with RNA was recent, I think they were desperate with Covid and released the vaccines, at which point everyone is now like…so we could have been curing things this whole time 👀

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liquidsunshine
43 minutes ago, JohnWayne92 said:

I don’t believe the break through with RNA was recent, I think they were desperate with Covid and released the vaccines, at which point everyone is now like…so we could have been curing things this whole time 👀

The research has been more than 50 years in the making- the lepid technology needed to the deliver the instruction was a recent breakthrough. 

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Lona Delery
3 hours ago, Gabi001 said:

Great news, but when will they give so much money and energy into HIV treatment and vaccine? 

they do? but HIV is an entirely different kind of virus which makes developing an actual vaccine/treatment a lot harder

Sometimes it feels like I've got a war in my mind, I wanna get off but I keep riding the ride
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RAMROD

That is so great! Hope it will also able to help people with long covid

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